InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Il10ra

Summary

InnateDB Protein

IDBP-159460.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Il10ra

Protein Name

interleukin 10 receptor, alpha

Synonyms

AW553859; CDw210; CDw210a; Il10r; mIL-10R;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000034594

InnateDB Gene

IDBG-159458 (Il10ra)

Protein Structure

UniProt Annotation

Function

Receptor for IL10; binds IL10 with a high affinity.

Subcellular Localization

Membrane; Single-pass type I membrane protein.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	2 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004920	interleukin-10 receptor activity
GO:0005515	protein binding
GO:0019969	interleukin-10 binding

Biological Process

GO:0019221	cytokine-mediated signaling pathway
GO:0032496	response to lipopolysaccharide

Cellular Component

GO:0005737	cytoplasm
GO:0005886	plasma membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:96538

InterPro

IPR003961 Fibronectin, type III

PFAM

PF00041
PF01108

PRINTS

PIRSF

SMART

SM00060

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q61727

PhosphoSite

PhosphoSite-

TrEMBL

Q3UDL4

UniProt Splice Variant

Entrez Gene

16154

UniGene

Mm.379327

RefSeq

NP_032374

MGI ID

MGI Symbol

Il10ra

OMIM

CCDS

CCDS23131

HPRD

IMGT

EMBL

AK137663 AK150022 AK159566 CH466522 L12120

GenPept

AAA16156 BAE23452 BAE29247 BAE35189 EDL25643