InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Zbtb20

Summary

InnateDB Protein

IDBP-161028.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Zbtb20

Protein Name

zinc finger and BTB domain containing 20

Synonyms

1300017A20Rik; 7330412A13Rik; A930017C21Rik; D16Wsu73e; DPZF; HOF; ODA-8S; Oda8; Zfp288;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000078410

InnateDB Gene

IDBG-161026 (Zbtb20)

Protein Structure

UniProt Annotation

Function

May be a transcription factor that may be involved in hematopoiesis, oncogenesis, and immune responses (By similarity). Binds to DNA. {ECO:0000250}.

Subcellular Localization

Nucleus {ECO:0000305PubMed:11744704}.

Disease Associations

Tissue Specificity

Specifically expressed in early hippocampal neurons, cerebellar granule cells and gliogenic progenitors as well as in differentiated glia. {ECO:0000269PubMed:11744704}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001078	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0003677	DNA binding
GO:0005515	protein binding
GO:0046872	metal ion binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0006351	transcription, DNA-templated
GO:0045087	innate immune response (InnateDB)