Mus musculus Gene: Zbtb20
Summary
InnateDB Gene IDBG-161026.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Zbtb20
Gene Name zinc finger and BTB domain containing 20
Synonyms 1300017A20Rik; 7330412A13Rik; A930017C21Rik; D16Wsu73e; DPZF; HOF; ODA-8S; Oda8; Zfp288;
Species Mus musculus
Ensembl Gene ENSMUSG00000022708
Encoded Proteins
zinc finger and BTB domain containing 20
zinc finger and BTB domain containing 20
zinc finger and BTB domain containing 20
zinc finger and BTB domain containing 20
zinc finger and BTB domain containing 20
zinc finger and BTB domain containing 20
zinc finger and BTB domain containing 20
zinc finger and BTB domain containing 20
zinc finger and BTB domain containing 20
zinc finger and BTB domain containing 20
zinc finger and BTB domain containing 20
zinc finger and BTB domain containing 20
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation
Summary
ZBTB20 inhibits transcription of IkBa to promote full TLR-triggered immunity. Zbtb20 null mice are resistant to endotoxin shock and sepsis.
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000181722:
Gene Information
Type Protein coding
Genomic Location Chromosome 16:42875881-43642602
Strand Forward strand
Band B4
Transcripts
ENSMUST00000079441 ENSMUSP00000078410
ENSMUST00000114695 ENSMUSP00000110343
ENSMUST00000114694 ENSMUSP00000110342
ENSMUST00000114691 ENSMUSP00000110339
ENSMUST00000114690 ENSMUSP00000110338
ENSMUST00000126354
ENSMUST00000131689
ENSMUST00000132881
ENSMUST00000151244 ENSMUSP00000124984
ENSMUST00000151290
ENSMUST00000146708 ENSMUSP00000125233
ENSMUST00000134537
ENSMUST00000141941
ENSMUST00000139491
ENSMUST00000156367 ENSMUSP00000124126
ENSMUST00000148775 ENSMUSP00000125016
ENSMUST00000126100 ENSMUSP00000125241
ENSMUST00000123047 ENSMUSP00000124798
ENSMUST00000156981 ENSMUSP00000124189
ENSMUST00000122875
ENSMUST00000162745
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001078 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006351 transcription, DNA-templated
GO:0045087 innate immune response (InnateDB)
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.136238 Mm.409116 Mm.421885 Mm.440841 Mm.441121 Mm.441425 Mm.441972 Mm.443780 Mm.445631 Mm.460947 Mm.463304 Mm.484303 Mm.487371 Mm.488718
RefSeq NM_001285805 NM_019778 NM_181058 XM_006522401 XM_006522402 XM_006522405 XM_006522406 XM_006522407 XM_006522408 XM_006522410 XM_006522411 XM_006522412 XM_006522413 XM_006522414 XM_006522415 XM_006522416 XM_006522417 XM_006522418 XM_006522419 XM_006522420 XM_006522421 XM_006522423 XM_006522424
OMIM
CCDS CCDS28178 CCDS49851
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas