Version 5.4
Mus musculus Gene: Zbtb20
Summary
InnateDB Gene IDBG-161026.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Zbtb20
Gene Name zinc finger and BTB domain containing 20
Synonyms 1300017A20Rik; 7330412A13Rik; A930017C21Rik; D16Wsu73e; DPZF; HOF; ODA-8S; Oda8; Zfp288
Species Mus musculus
Ensembl Gene ENSMUSG00000022708
Encoded Proteins
IDBP-161028
zinc finger and BTB domain containing 20
IDBP-251226
zinc finger and BTB domain containing 20
IDBP-251228
zinc finger and BTB domain containing 20
IDBP-251230
zinc finger and BTB domain containing 20
IDBP-251232
zinc finger and BTB domain containing 20
IDBP-531614
zinc finger and BTB domain containing 20
IDBP-539654
zinc finger and BTB domain containing 20
IDBP-531706
zinc finger and BTB domain containing 20
IDBP-542395
zinc finger and BTB domain containing 20
IDBP-540086
zinc finger and BTB domain containing 20
IDBP-533071
zinc finger and BTB domain containing 20
IDBP-537456
zinc finger and BTB domain containing 20
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation
Summary
PMID 23776228
ZBTB20 inhibits transcription of IkBa to promote full TLR-triggered immunity. Zbtb20 null mice are resistant to endotoxin shock and sepsis.
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000181722:
Gene Information
Type Protein coding
Genomic Location Chromosome 16:42875881-43642602
Strand Forward strand
Band B4
Transcripts
ENSMUST00000079441 ENSMUSP00000078410
ENSMUST00000114695 ENSMUSP00000110343
ENSMUST00000114694 ENSMUSP00000110342
ENSMUST00000114691 ENSMUSP00000110339
ENSMUST00000114690 ENSMUSP00000110338
ENSMUST00000126354
ENSMUST00000131689
ENSMUST00000132881
ENSMUST00000151244 ENSMUSP00000124984
ENSMUST00000151290
ENSMUST00000146708 ENSMUSP00000125233
ENSMUST00000134537
ENSMUST00000141941
ENSMUST00000139491
ENSMUST00000156367 ENSMUSP00000124126
ENSMUST00000148775 ENSMUSP00000125016
ENSMUST00000126100 ENSMUSP00000125241
ENSMUST00000123047 ENSMUSP00000124798
ENSMUST00000156981 ENSMUSP00000124189
ENSMUST00000122875
ENSMUST00000162745
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001078 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006351 transcription, DNA-templated
GO:0045087 innate immune response (InnateDB)
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000181722
View Gene Order
ENSBTAG00000011928
Not yet available
Cross-References
SwissProt Q8K0L9
TrEMBL E0CX28 E0CXK1 E0CXT9 E0CYH3 E0CYJ9 Q8CAI3
UniProt Splice Variant
Entrez Gene 56490
UniGene Mm.136238 Mm.409116 Mm.421885 Mm.440841 Mm.441121 Mm.441425 Mm.441972 Mm.443780 Mm.445631 Mm.460947 Mm.463304 Mm.484303 Mm.487371 Mm.488718
RefSeq NM_001285805 NM_019778 NM_181058 XM_006522401 XM_006522402 XM_006522405 XM_006522406 XM_006522407 XM_006522408 XM_006522410 XM_006522411 XM_006522412 XM_006522413 XM_006522414 XM_006522415 XM_006522416 XM_006522417 XM_006522418 XM_006522419 XM_006522420 XM_006522421 XM_006522423 XM_006522424
OMIM
CCDS CCDS28178 CCDS49851
HPRD
IMGT
MGI ID MGI:1929213
MGI Symbol Zbtb20
EMBL AC112150 AC120871 AC158170 AC161607 AC174777 AF194030 AK005028 AK038731 BC031114 BC056446 CT010512 CT010517
GenPept AAF06015 AAH31114 AAH56446 BAB23755 BAC30112 CAO77851 CAO77852
RNA Seq Atlas 56490

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca