Version 5.4
Homo sapiens Protein: SOD1
Summary
InnateDB Protein IDBP-1615.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SOD1
Protein Name superoxide dismutase 1, soluble
Synonyms ALS; ALS1; HEL-S-44; homodimer; hSod1; IPOA; SOD;
Species Homo sapiens
Ensembl Protein ENSP00000374645
InnateDB Gene IDBG-1609 (SOD1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 84 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated
Total 84 [view]
Protein-Protein 76 [view]
Protein-DNA 8 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004784 superoxide dismutase activity
GO:0046872 metal ion binding
Biological Process
GO:0006801 superoxide metabolic process
GO:0019430 removal of superoxide radicals
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR001424 Superoxide dismutase, copper/zinc binding domain
PFAM PF00080
PRINTS PR00068
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL X5D5A9
UniProt Splice Variant
Entrez Gene 6647
UniGene
RefSeq
HUGO HGNC:11179
OMIM 147450
CCDS
HPRD 00937
IMGT
EMBL AP000253 AP000254 KJ194105 KJ201029
GenPept AHW49384 AHW49388

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca