Version 5.4
Homo sapiens Protein: SNX1
Summary
InnateDB Protein IDBP-16213.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SNX1
Protein Name sorting nexin 1
Synonyms HsT17379; VPS5;
Species Homo sapiens
Ensembl Protein ENSP00000261889
InnateDB Gene IDBG-16207 (SNX1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 58 experimentally validated interaction(s) in this database.
Experimentally validated
Total 58 [view]
Protein-Protein 55 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0035091 phosphatidylinositol binding
Biological Process
GO:0006886 intracellular protein transport
GO:0006897 endocytosis
GO:0016197 endosomal transport
GO:0034498 early endosome to Golgi transport
GO:0042147 retrograde transport, endosome to Golgi
GO:0045732 positive regulation of protein catabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005768 endosome
GO:0005769 early endosome
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0010008 endosome membrane
GO:0016020 membrane
GO:0016023 cytoplasmic membrane-bounded vesicle
GO:0030904 retromer complex
GO:0031901 early endosome membrane
GO:0043231 intracellular membrane-bounded organelle
Protein Structure and Domains
PDB ID
InterPro IPR001683 Phox homologous domain
IPR005329 Sorting nexin, N-terminal
IPR015404 Vps5 C-terminal
PFAM PF00787
PF03700
PF09325
PRINTS
PIRSF
SMART SM00312
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q13596
PhosphoSite PhosphoSite-Q13596
TrEMBL H0YKT3
UniProt Splice Variant
Entrez Gene 6642
UniGene Hs.703547
RefSeq NP_001229862
HUGO HGNC:11172
OMIM 601272
CCDS CCDS58371
HPRD 03171
IMGT
EMBL AC021541 AC100840 AF065483 AF065484 AK128179 AK291752 BC000357 BT006983 CH471082 U53225
GenPept AAA98672 AAC17182 AAC17183 AAH00357 AAP35629 BAC87312 BAF84441 EAW77663 EAW77665

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca