Version 5.4
Mus musculus Protein: Ddt
Summary
InnateDB Protein IDBP-163708.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ddt
Protein Name D-dopachrome tautomerase
Synonyms C78655;
Species Mus musculus
Ensembl Protein ENSMUSP00000001716
InnateDB Gene IDBG-163706 (Ddt)
Protein Structure
UniProt Annotation
Function Tautomerization of D-dopachrome with decarboxylation to give 5,6-dihydroxyindole (DHI). {ECO:0000250}.
Subcellular Localization Cytoplasm.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0033981 D-dopachrome decarboxylase activity
Biological Process
GO:0042438 melanin biosynthetic process
Cellular Component
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:1298381
InterPro IPR001398 Macrophage migration inhibitory factor
IPR014347 Tautomerase/MIF superfamily
PFAM PF01187
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O35215
PhosphoSite PhosphoSite-O35215
TrEMBL Q3UNI8
UniProt Splice Variant
Entrez Gene 13202
UniGene
RefSeq NP_034157
MGI ID 3KER
MGI Symbol Ddt
OMIM
CCDS CCDS23930
HPRD
IMGT
EMBL AC142499 AF012431 AF068199 AK144193 BC010753 CH466553
GenPept AAC32825 AAC77467 AAH10753 BAE25759 EDL31890

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca