Version 5.4
Mus musculus Protein: Pdlim1
Summary
InnateDB Protein IDBP-164552.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pdlim1
Protein Name PDZ and LIM domain 1 (elfin)
Synonyms Clim1; CLP36; mClim1;
Species Mus musculus
Ensembl Protein ENSMUSP00000064545
InnateDB Gene IDBG-164550 (Pdlim1)
Protein Structure
UniProt Annotation
Function Cytoskeletal protein that may act as an adapter that brings other proteins (like kinases) to the cytoskeleton. {ECO:0000250}.
Subcellular Localization Cytoplasm, cytoskeleton {ECO:0000269PubMed:11596114}. Note=Associates with the actin stress fibers.
Disease Associations
Tissue Specificity Expressed in heart, lung, spleen, testis and skeletal muscle. {ECO:0000269PubMed:11596114}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.
Experimentally validated
Total 11 [view]
Protein-Protein 11 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 17 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003713 transcription coactivator activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
Biological Process
GO:0001666 response to hypoxia
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005667 transcription factor complex
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
Protein Structure and Domains
PDB ID MGI:1860611
InterPro IPR001478 PDZ domain
IPR001781 Zinc finger, LIM-type
IPR006643 ZASP
PFAM PF00595
PF13180
PF00412
PRINTS
PIRSF
SMART SM00228
SM00132
SM00735
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O70400
PhosphoSite PhosphoSite-O70400
TrEMBL S4R1V0
UniProt Splice Variant
Entrez Gene 54132
UniGene
RefSeq NP_058557
MGI ID
MGI Symbol Pdlim1
OMIM
CCDS CCDS37977
HPRD
IMGT
EMBL AC170187 AF053367 AK076285 AK088089 AK146225 BC004809
GenPept AAC08436 AAH04809 BAC36288 BAC40138 BAE26993

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca