InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Fbln5

Summary

InnateDB Protein

IDBP-165158.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Fbln5

Protein Name

fibulin 5

Synonyms

A55; DANCE; EVEC;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000021603

InnateDB Gene

IDBG-165156 (Fbln5)

Protein Structure

UniProt Annotation

Function

Promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. Could be a vascular ligand for integrin receptors and may play a role in vascular development and remodeling.

Subcellular Localization

Secreted.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	11 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005509	calcium ion binding
GO:0005515	protein binding
GO:0008022	protein C-terminus binding

Biological Process

GO:0001558	regulation of cell growth
GO:0007155	cell adhesion
GO:0030198	extracellular matrix organization
GO:0034394	protein localization to cell surface
GO:0048251	elastic fiber assembly
GO:2000121	regulation of removal of superoxide radicals

Cellular Component

GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0005737	cytoplasm
GO:0031012	extracellular matrix
GO:0070062	extracellular vesicular exosome
GO:0071953	elastic fiber