Mus musculus Protein: Irx1 | |||||||||
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Summary | |||||||||
InnateDB Protein | IDBP-165336.6 | ||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
Gene Symbol | Irx1 | ||||||||
Protein Name | Iroquois related homeobox 1 (Drosophila) | ||||||||
Synonyms | |||||||||
Species | Mus musculus | ||||||||
Ensembl Protein | ENSMUSP00000076562 | ||||||||
InnateDB Gene | IDBG-165334 (Irx1) | ||||||||
Protein Structure | |||||||||
UniProt Annotation | |||||||||
Function | |||||||||
Subcellular Localization | Nucleus {ECO:0000305}. | ||||||||
Disease Associations | |||||||||
Tissue Specificity | Expressed in specific and overlapping patterns with Irx1 and Irx2 in the developing and adult metanephric kidney. In the adult metanephros, renal expression is found in the loop of Henle in the S3 proximal tubule segment and in the thick ascending limb (TAL) of the distal tubule. {ECO:0000269PubMed:17875669}. | ||||||||
Comments | |||||||||
Interactions | |||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Protein Structure and Domains | |||||||||
PDB ID | MGI:1197515 | ||||||||
InterPro |
IPR001356
Homeobox domain IPR003893 Iroquois-class homeodomain protein IPR009057 Homeodomain-like |
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PFAM |
PF00046
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PRINTS | |||||||||
PIRSF | |||||||||
SMART |
SM00389
SM00548 |
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TIGRFAMs | |||||||||
Post-translational Modifications | |||||||||
Modification | |||||||||
Cross-References | |||||||||
SwissProt | P81068 | ||||||||
PhosphoSite | PhosphoSite-P81068 | ||||||||
TrEMBL | |||||||||
UniProt Splice Variant | |||||||||
Entrez Gene | 16371 | ||||||||
UniGene | Mm.402685 | ||||||||
RefSeq | NP_034703 | ||||||||
MGI ID | |||||||||
MGI Symbol | Irx1 | ||||||||
OMIM | |||||||||
CCDS | CCDS26627 | ||||||||
HPRD | |||||||||
IMGT | |||||||||
EMBL | AF165984 AK133937 CH466563 CT009684 Y15002 | ||||||||
GenPept | AAF63954 BAE21938 CAA75234 EDL37041 | ||||||||