Mus musculus Gene: Irx1
Summary
InnateDB Gene IDBG-165334.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Irx1
Gene Name Iroquois related homeobox 1 (Drosophila)
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000060969
Encoded Proteins
Iroquois related homeobox 1 (Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000170549:
This gene encodes a member of the Iroquois homeobox protein family. Homeobox genes in this family are involved in pattern formation in the embryo. The gene product has been identified as a tumor suppressor in gastric (PMID: 21602894, 20440264) and head and neck cancers (PMID: 18559491). A pseudogene of this gene is located on chromosome 13. [provided by RefSeq, Dec 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:71957921-71963723
Strand Reverse strand
Band C1
Transcripts
ENSMUST00000077337 ENSMUSP00000076562
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0001656 metanephros development
GO:0006355 regulation of transcription, DNA-templated
GO:0072086 specification of loop of Henle identity
GO:0072272 proximal/distal pattern formation involved in metanephric nephron development
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt P81068
TrEMBL
UniProt Splice Variant
Entrez Gene 16371
UniGene Mm.316056 Mm.402685
RefSeq NM_010573
OMIM
CCDS CCDS26627
HPRD
IMGT
MGI ID MGI:1197515
MGI Symbol Irx1
EMBL AF165984 AK133937 CH466563 CT009684 Y15002
GenPept AAF63954 BAE21938 CAA75234 EDL37041
RNA Seq Atlas 16371