InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Col18a1

Summary

InnateDB Protein

IDBP-166548.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Col18a1

Protein Name

collagen, type XVIII, alpha 1

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000072538

InnateDB Gene

IDBG-166544 (Col18a1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005198	structural molecule activity
GO:0005515	protein binding
GO:0042802	identical protein binding

Biological Process

GO:0001525	angiogenesis
GO:0001886	endothelial cell morphogenesis
GO:0007155	cell adhesion
GO:0008284	positive regulation of cell proliferation
GO:0016055	Wnt signaling pathway
GO:0030198	extracellular matrix organization
GO:0030335	positive regulation of cell migration
GO:0042493	response to drug
GO:0051599	response to hydrostatic pressure
GO:2000353	positive regulation of endothelial cell apoptotic process

Cellular Component

GO:0005581	collagen trimer
GO:0005604	basement membrane
GO:0005615	extracellular space
GO:0031012	extracellular matrix

Protein Structure and Domains

PDB ID

MGI:88451

InterPro

IPR001791 Laminin G domain
IPR008160 Collagen triple helix repeat
IPR008985 Concanavalin A-like lectin/glucanases superfamily
IPR010363 Domain of unknown function DUF959, collagen XVIII, N-terminal
IPR010515 Collagenase NC10/endostatin
IPR016187 C-type lectin fold
IPR020067 Frizzled domain

PFAM

PF00054
PF02210
PF01391
PF06121
PF06482
PF01392

PRINTS

PIRSF

SMART

SM00210
SM00282
SM00063

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite