Version 5.4
Mus musculus Protein: Rpn1
Summary
InnateDB Protein IDBP-166700.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rpn1
Protein Name ribophorin I
Synonyms AU018702; D6Wsu137e; Rpn-1;
Species Mus musculus
Ensembl Protein ENSMUSP00000032143
InnateDB Gene IDBG-166698 (Rpn1)
Protein Structure
UniProt Annotation
Function Essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. {ECO:0000250}.
Subcellular Localization Endoplasmic reticulum membrane; Single-pass type I membrane protein. Melanosome {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 50 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 3 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 50 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006486 protein glycosylation
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0042470 melanosome
Protein Structure and Domains
PDB ID MGI:98084
InterPro IPR007676 Ribophorin I
IPR029057 Phosphoribosyltransferase-like
PFAM PF04597
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q91YQ5
PhosphoSite PhosphoSite-Q91YQ5
TrEMBL Q99LY0
UniProt Splice Variant
Entrez Gene 103963
UniGene Mm.402349
RefSeq NP_598694
MGI ID
MGI Symbol Rpn1
OMIM
CCDS CCDS20332
HPRD
IMGT
EMBL AK052130 AK132750 AK151899 AK153867 BC002175 BC016080 BC085483
GenPept AAH02175 AAH16080 AAH85483 BAC34853 BAE21332 BAE30782 BAE32221

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca