InnateDB Protein
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IDBP-167786.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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S100a13
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Protein Name
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S100 calcium binding protein A13
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Synonyms
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000047737
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InnateDB Gene
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IDBG-167784 (S100a13)
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Protein Structure
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Function |
Plays a role in the export of proteins that lack a signal peptide and are secreted by an alternative pathway. Binds two calcium ions per subunit. Binds one copper ion. Binding of one copper ion does not interfere with calcium binding. Required for the copper-dependent stress-induced export of IL1A and FGF1. The calcium-free protein binds to lipid vesicles containing phosphatidylserine, but not to vesicles containing phosphatidylcholine. {ECO:0000269PubMed:11432880, ECO:0000269PubMed:12746488, ECO:0000269PubMed:17991455}.
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Subcellular Localization |
Cytoplasm. Secreted. Note=Secretion is mediated by exposure to stress and requires copper ions.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Experimentally validated |
Total |
3
[view]
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Protein-Protein |
3
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
10 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:109581
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InterPro |
IPR013787
S100/CaBP-9k-type, calcium binding, subdomain
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PFAM |
PF01023
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
P97352
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PhosphoSite |
PhosphoSite-P97352
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TrEMBL |
Q545H7
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UniProt Splice Variant |
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Entrez Gene |
20196
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UniGene |
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RefSeq |
NP_033139
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MGI ID |
2CXJ
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MGI Symbol |
S100a13
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OMIM |
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CCDS |
CCDS38504
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HPRD |
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IMGT |
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EMBL |
AK002755
AK008895
BC005687
CH466547
X99921
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GenPept |
AAH05687
BAB22332
BAB25958
CAA68189
EDL15124
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