Mus musculus Protein: Tec
Summary
InnateDB Protein IDBP-170171.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tec
Protein Name tec protein tyrosine kinase
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000071836
InnateDB Gene IDBG-170167 (Tec)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 31 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 31 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0006468 protein phosphorylation
GO:0007229 integrin-mediated signaling pathway
GO:0010543 regulation of platelet activation
GO:0018108 peptidyl-tyrosine phosphorylation
GO:0035556 intracellular signal transduction
GO:0042246 tissue regeneration
GO:0050853 B cell receptor signaling pathway
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005911 cell-cell junction
Protein Structure and Domains
PDB ID MGI:98662
InterPro IPR000719 Protein kinase domain
IPR000980 SH2 domain
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR001452 SH3 domain
IPR001562 Zinc finger, Btk motif
IPR001849 Pleckstrin homology domain
IPR002290 Serine/threonine- /dual specificity protein kinase, catalytic domain
IPR011009 Protein kinase-like domain
IPR011511 Variant SH3 domain
IPR020635 Tyrosine-protein kinase, catalytic domain
PFAM PF00069
PF00017
PF14633
PF07714
PF00018
PF14604
PF00779
PF00169
PF07653
PRINTS PR00401
PR00109
PR00452
PR00402
PIRSF
SMART SM00252
SM00326
SM00107
SM00233
SM00220
SM00219
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q3U436
UniProt Splice Variant
Entrez Gene 21682
UniGene Mm.319581
RefSeq NP_001106931
MGI ID
MGI Symbol Tec
OMIM
CCDS CCDS51516
HPRD
IMGT
EMBL AC099698 AC158939 AK139329 AK154457 BC062884
GenPept AAH62884 BAE23957 BAE32599