InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: H2-DMb2

Summary

InnateDB Protein

IDBP-170495.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

H2-DMb2

Protein Name

histocompatibility 2, class II, locus Mb2

Synonyms

H-2Mb2; H2-Mb2;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000043526

InnateDB Gene

IDBG-170493 (H2-DMb2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	2 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	6 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0006955	immune response
GO:0019882	antigen processing and presentation
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0051085	chaperone mediated protein folding requiring cofactor

Cellular Component

GO:0005764	lysosome
GO:0005765	lysosomal membrane
GO:0005770	late endosome
GO:0005771	multivesicular body
GO:0010008	endosome membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0042613	MHC class II protein complex

Protein Structure and Domains

PDB ID

MGI:95923

InterPro

IPR000353 MHC class II, beta chain, N-terminal
IPR003597 Immunoglobulin C1-set
IPR007110 Immunoglobulin-like domain
IPR011162 MHC classes I/II-like antigen recognition protein
IPR013162 CD80-like, immunoglobulin C2-set

PFAM

PF00969
PF07654
PF08205

PRINTS

PIRSF

SMART

SM00921
SM00407

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite