InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Tap1

Summary

InnateDB Protein

IDBP-170618.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Tap1

Protein Name

transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)

Synonyms

ABC17; Abcb2; APT1; Ham-1; Ham1; MTP1; PSF1; RING4; TAP; Tap-1; Y3;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000039264

InnateDB Gene

IDBG-170616 (Tap1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 31 interaction(s) predicted by orthology.

Experimentally validated
Total	13 [view]
Protein-Protein	6 [view]
Protein-DNA	7 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	31 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0005524	ATP binding
GO:0015197	peptide transporter activity
GO:0016887	ATPase activity
GO:0017111	nucleoside-triphosphatase activity
GO:0042288	MHC class I protein binding
GO:0042626	ATPase activity, coupled to transmembrane movement of substances

Biological Process

GO:0006200	ATP catabolic process
GO:0006810	transport
GO:0006952	defense response
GO:0015833	peptide transport
GO:0055085	transmembrane transport

Cellular Component

GO:0005739	mitochondrion
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:98483

InterPro

IPR001140 ABC transporter, transmembrane domain
IPR003439 ABC transporter-like
IPR003593 AAA+ ATPase domain
IPR011527 ABC transporter type 1, transmembrane domain
IPR013305 ABC transporter, ABCB2
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00664
PF13748
PF00005

PRINTS

PR01896

PIRSF

SMART

SM00382

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt