InnateDB Protein
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IDBP-171212.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Mgea5
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Protein Name
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meningioma expressed antigen 5 (hyaluronidase)
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Synonyms
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2810009A20Rik; 4833427O07Rik; 5830447M11Rik; AA408215; Hy5; mKIAA0679; Ncoat;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000026243
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InnateDB Gene
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IDBG-171210 (Mgea5)
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Protein Structure
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Function |
Cleaves GlcNAc but not GalNAc from glycopeptides. Can use p-nitrophenyl-beta-GlcNAc as substrate but not p-nitrophenyl- beta-GalNAc or p-nitrophenyl-alpha-GlcNAc. Possesses hyaluronidase activity (By similarity). Acetylates 'Lys-8' of histone H4. {ECO:0000250, ECO:0000269PubMed:16356930}.
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Subcellular Localization |
Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.
Experimentally validated |
Total |
5
[view]
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Protein-Protein |
5
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
18 [view]
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Molecular Function |
Accession |
GO Term |
GO:0004402
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histone acetyltransferase activity
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GO:0016798
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hydrolase activity, acting on glycosyl bonds
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1932139
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InterPro |
IPR011496
Beta-N-acetylglucosaminidase
IPR016181
Acyl-CoA N-acyltransferase
IPR017853
Glycoside hydrolase, superfamily
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PFAM |
PF07555
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9EQQ9
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PhosphoSite |
PhosphoSite-Q9EQQ9
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TrEMBL |
Q9CU60
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UniProt Splice Variant |
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Entrez Gene |
76055
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UniGene |
Mm.490674
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RefSeq |
NP_076288
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MGI ID |
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MGI Symbol |
Mgea5
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OMIM |
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CCDS |
CCDS29866
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HPRD |
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IMGT |
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EMBL |
AF132214
AK012695
AK014781
AK017997
AK077613
AK088774
AK129188
AK145227
BC041109
BC054821
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GenPept |
AAG43273
AAH41109
AAH54821
BAB28416
BAB29550
BAB31029
BAC36900
BAC40564
BAC97998
BAE26311
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