Mus musculus Protein: Gla
Summary
InnateDB Protein IDBP-171559.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gla
Protein Name galactosidase, alpha
Synonyms Ags;
Species Mus musculus
Ensembl Protein ENSMUSP00000033621
InnateDB Gene IDBG-171557 (Gla)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Lysosome.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0004557 alpha-galactosidase activity
GO:0005102 receptor binding
GO:0005515 protein binding
GO:0016936 galactoside binding
GO:0042803 protein homodimerization activity
GO:0052692 raffinose alpha-galactosidase activity
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0009311 oligosaccharide metabolic process
GO:0016139 glycoside catabolic process
GO:0045019 negative regulation of nitric oxide biosynthetic process
GO:0046477 glycosylceramide catabolic process
GO:0051001 negative regulation of nitric-oxide synthase activity
Cellular Component
GO:0005576 extracellular region
GO:0005737 cytoplasm
GO:0005764 lysosome
GO:0005794 Golgi apparatus
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID MGI:1347344
InterPro IPR000111 Glycoside hydrolase, clan GH-D
IPR002241 Glycoside hydrolase, family 27
IPR017853 Glycoside hydrolase, superfamily
PFAM PF02065
PRINTS PR00740
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P51569
PhosphoSite PhosphoSite-P51569
TrEMBL Q8BGZ6
UniProt Splice Variant
Entrez Gene 11605
UniGene
RefSeq NP_038491
MGI ID
MGI Symbol Gla
OMIM
CCDS CCDS41124
HPRD
IMGT
EMBL AK040081 AK054547 AK164231 BC009021 BX004852 L46651 U34071 U50715 U50716 U58105
GenPept AAA74453 AAA96749 AAB47244 AAC52583 AAC52584 AAH09021 BAC30508 BAC35819 BAE37692