Version 5.4
Mus musculus Protein: Rasgrf2
Summary
InnateDB Protein IDBP-171771.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol Rasgrf2
Protein Name RAS protein-specific guanine nucleotide-releasing factor 2
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000096930
InnateDB Gene IDBG-171717 (Rasgrf2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005089 Rho guanyl-nucleotide exchange factor activity
GO:0005515 protein binding
Biological Process
GO:0007264 small GTPase mediated signal transduction
GO:0032319 regulation of Rho GTPase activity
GO:0035023 regulation of Rho protein signal transduction
GO:0051056 regulation of small GTPase mediated signal transduction
GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity
Cellular Component
GO:0005622 intracellular
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:109137
InterPro IPR000048 IQ motif, EF-hand binding site
IPR000219 Dbl homology (DH) domain
IPR000651 Ras-like guanine nucleotide exchange factor, N-terminal
IPR001849 Pleckstrin homology domain
IPR001895 Guanine-nucleotide dissociation stimulator CDC25
IPR023578 Ras guanine nucleotide exchange factor, domain
PFAM PF00612
PF00621
PF00618
PF00169
PF00617
PRINTS
PIRSF
SMART SM00015
SM00325
SM00229
SM00233
SM00147
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL D3Z6K8
UniProt Splice Variant
Entrez Gene
UniGene Mm.428879
RefSeq
MGI ID
MGI Symbol Rasgrf2
OMIM
CCDS
HPRD
IMGT
EMBL AC146698 AC164622 AC167972 CAAA01123268 CAAA01123273 CAAA01123277
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca