Mus musculus Protein: Tecr
Summary
InnateDB Protein IDBP-172187.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tecr
Protein Name trans-2,3-enoyl-CoA reductase
Synonyms 2410016D23Rik; A230102P12Rik; AI173355; D17Ertd178e; Gpsn2; SC2;
Species Mus musculus
Ensembl Protein ENSMUSP00000019382
InnateDB Gene IDBG-172185 (Tecr)
Protein Structure
UniProt Annotation
Function Reduces trans-2,3-stearoyl-CoA to stearoyl-CoA of long and very long chain fatty acids. {ECO:0000250}.
Subcellular Localization Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 13 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors
Biological Process
GO:0006629 lipid metabolic process
GO:0006694 steroid biosynthetic process
GO:0030497 fatty acid elongation
GO:0042761 very long-chain fatty acid biosynthetic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005737 cytoplasm
GO:0016021 integral component of membrane
GO:0030176 integral component of endoplasmic reticulum membrane
Protein Structure and Domains
PDB ID MGI:1915408
InterPro IPR001104 3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal
IPR029071 Ubiquitin-related domain
PFAM PF02544
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9CY27
PhosphoSite PhosphoSite-Q9CY27
TrEMBL Q3TAN8
UniProt Splice Variant
Entrez Gene 106529
UniGene
RefSeq NP_598879
MGI ID
MGI Symbol Tecr
OMIM
CCDS CCDS40403
HPRD
IMGT
EMBL AK010984 AK171718 BC019984 BC115455
GenPept AAH19984 AAI15456 BAB27305 BAE42630