Version 5.4
Mus musculus Protein: Kcne4
Summary
InnateDB Protein IDBP-172810.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Kcne4
Protein Name potassium voltage-gated channel, Isk-related subfamily, gene 4
Synonyms AW487937; MiRP3;
Species Mus musculus
Ensembl Protein ENSMUSP00000055415
InnateDB Gene IDBG-172808 (Kcne4)
Protein Structure
UniProt Annotation
Function Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Associated with KCNQ1/KVLTQ1 inhibits potassium current (By similarity). {ECO:0000250}.
Subcellular Localization Membrane; Single-pass type I membrane protein.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005249 voltage-gated potassium channel activity
GO:0005267 potassium channel activity
Biological Process
GO:0006811 ion transport
GO:0034765 regulation of ion transmembrane transport
GO:0071805 potassium ion transmembrane transport
Cellular Component
GO:0008076 voltage-gated potassium channel complex
GO:0016020 membrane
GO:0016324 apical plasma membrane
Protein Structure and Domains
PDB ID MGI:1891125
InterPro IPR000369 Potassium channel, voltage-dependent, beta subunit, KCNE
PFAM PF02060
PRINTS PR00168
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9WTW3
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 57814
UniGene Mm.410369
RefSeq NP_067317
MGI ID
MGI Symbol Kcne4
OMIM
CCDS CCDS15088
HPRD
IMGT
EMBL AF076533 BC032920
GenPept AAD28091 AAH32920

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca