Version 5.4
Mus musculus Gene: Kcne4
Summary
InnateDB Gene IDBG-172808.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Kcne4
Gene Name potassium voltage-gated channel, Isk-related subfamily, gene 4
Synonyms AW487937; MiRP3
Species Mus musculus
Ensembl Gene ENSMUSG00000047330
Encoded Proteins
IDBP-172810
potassium voltage-gated channel, Isk-related subfamily, gene 4
IDBP-789299
potassium voltage-gated channel, Isk-related subfamily, gene 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000152049:
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, isk-related subfamily. This member is a type I membrane protein, and a beta subunit that assembles with a potassium channel alpha-subunit to modulate the gating kinetics and enhance stability of the multimeric complex. This gene is prominently expressed in the embryo and in adult uterus. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:78816758-78820028
Strand Forward strand
Band C4
Transcripts
ENSMUST00000057262 ENSMUSP00000055415
ENSMUST00000187432 ENSMUSP00000140235
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005249 voltage-gated potassium channel activity
GO:0005267 potassium channel activity
Biological Process
GO:0006811 ion transport
GO:0034765 regulation of ion transmembrane transport
GO:0071805 potassium ion transmembrane transport
Cellular Component
GO:0008076 voltage-gated potassium channel complex
GO:0016020 membrane
GO:0016324 apical plasma membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000152049
View Gene Order
ENSBTAG00000006432
Not yet available
Cross-References
SwissProt Q9WTW3
TrEMBL
UniProt Splice Variant
Entrez Gene 57814
UniGene Mm.24386 Mm.410369
RefSeq NM_021342
OMIM
CCDS CCDS15088
HPRD
IMGT
MGI ID MGI:1891125
MGI Symbol Kcne4
EMBL AF076533 BC032920
GenPept AAD28091 AAH32920
RNA Seq Atlas 57814

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca