Mus musculus Protein: Ctss
Summary
InnateDB Protein IDBP-172852.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol Ctss
Protein Name cathepsin S
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000015667
InnateDB Gene IDBG-172850 (Ctss)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 0
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001968 fibronectin binding
GO:0004197 cysteine-type endopeptidase activity
GO:0005518 collagen binding
GO:0008233 peptidase activity
GO:0008234 cysteine-type peptidase activity
GO:0043236 laminin binding
GO:0043394 proteoglycan binding
Biological Process
GO:0002250 adaptive immune response
GO:0006508 proteolysis
GO:0030574 collagen catabolic process
GO:0034769 basement membrane disassembly
GO:0045087 innate immune response (InnateDB)
GO:0050729 positive regulation of inflammatory response
GO:0051603 proteolysis involved in cellular protein catabolic process
GO:0097067 cellular response to thyroid hormone stimulus
Cellular Component
GO:0005615 extracellular space
GO:0005764 lysosome
GO:0016020 membrane
GO:0043231 intracellular membrane-bounded organelle
Protein Structure and Domains
PDB ID MGI:107341
InterPro IPR000668 Peptidase C1A, papain C-terminal
IPR013201 Proteinase inhibitor I29, cathepsin propeptide
PFAM PF00112
PF08246
PRINTS PR00705
PIRSF
SMART SM00645
SM00848
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q3UD32
UniProt Splice Variant
Entrez Gene 13040
UniGene Mm.402416
RefSeq NP_001254624
MGI ID
MGI Symbol Ctss
OMIM
CCDS CCDS71291
HPRD
IMGT
EMBL AC092203 AK150274 AK150758 AK150842 AK152618
GenPept BAE29430 BAE29827 BAE29900 BAE31361