InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Bhmt2

Summary

InnateDB Protein

IDBP-173018.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Bhmt2

Protein Name

betaine-homocysteine methyltransferase 2

Synonyms

C81077; D13Ucla2;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000015941

InnateDB Gene

IDBG-173016 (Bhmt2)

Protein Structure

UniProt Annotation

Function

Involved in the regulation of homocysteine metabolism. Converts homocysteine to methionine using S-methylmethionine (SMM) as a methyl donor. {ECO:0000269PubMed:18230605}.

Subcellular Localization

Disease Associations

Tissue Specificity

Expressed in fetal heart, lung, liver, kidney and eye. {ECO:0000269PubMed:11087663}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008270	zinc ion binding
GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity
GO:0047150	betaine-homocysteine S-methyltransferase activity
GO:0061627	S-methylmethionine-homocysteine S-methyltransferase activity

Biological Process

GO:0009086	methionine biosynthetic process
GO:0032259	methylation
GO:0033477	S-methylmethionine metabolic process
GO:0046500	S-adenosylmethionine metabolic process
GO:0071267	L-methionine salvage