InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ltn1

Summary

InnateDB Protein

IDBP-173341.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ltn1

Protein Name

listerin E3 ubiquitin protein ligase 1

Synonyms

4930528H02Rik; AV266914; C87237; Listerin; Rnf160; Zfp294;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000038775

InnateDB Gene

IDBG-173339 (Ltn1)

Protein Structure

UniProt Annotation

Function

E3 ubiquitin-protein ligase. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. {ECO:0000269PubMed:19196968}.

Subcellular Localization

Disease Associations

Tissue Specificity

Wifely expressed, including in the brain and spinal cord. {ECO:0000269PubMed:19196968}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	10 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004842	ubiquitin-protein transferase activity
GO:0005488	binding
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0016874	ligase activity
GO:0046872	metal ion binding