InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Apom

Summary

InnateDB Protein

IDBP-176788.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Apom

Protein Name

apolipoprotein M

Synonyms

1190010O19Rik; G3a; NG20;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000025249

InnateDB Gene

IDBG-176786 (Apom)

Protein Structure

UniProt Annotation

Function

Probably involved in lipid transport. Can bind sphingosine-1-phosphate, myristic acid, palmitic acid and stearic acid, retinol, all-trans-retinoic acid and 9-cis-retinoic acid (By similarity). {ECO:0000250}.

Subcellular Localization

Secreted {ECO:0000305}.

Disease Associations

Tissue Specificity

Expressed by the liver; secreted in plasma.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005319	lipid transporter activity
GO:0005543	phospholipid binding
GO:0016209	antioxidant activity

Biological Process

GO:0009749	response to glucose
GO:0033344	cholesterol efflux
GO:0034375	high-density lipoprotein particle remodeling
GO:0034380	high-density lipoprotein particle assembly
GO:0034384	high-density lipoprotein particle clearance
GO:0034445	negative regulation of plasma lipoprotein particle oxidation
GO:0042157	lipoprotein metabolic process
GO:0043691	reverse cholesterol transport

Cellular Component

GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0034361	very-low-density lipoprotein particle
GO:0034362	low-density lipoprotein particle
GO:0034364	high-density lipoprotein particle
GO:0034365	discoidal high-density lipoprotein particle
GO:0034366	spherical high-density lipoprotein particle
GO:0070062	extracellular vesicular exosome