InnateDB Protein
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IDBP-178160.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Marveld2
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Protein Name
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MARVEL (membrane-associating) domain containing 2
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Synonyms
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000022137
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InnateDB Gene
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IDBG-178158 (Marveld2)
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Protein Structure
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Function |
Plays a role in the formation of the epithelial barriers. The separation of the endolymphatic and perilymphatic spaces of the organ of Corti from one another by epithelial barriers is required for normal hearing. {ECO:0000269PubMed:16365161}.
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Subcellular Localization |
Cell membrane; Multi-pass membrane protein. Cell junction, tight junction. Note=Found at tricellular contacts.
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Disease Associations |
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Tissue Specificity |
Predominently localized to small intestine, stomach and kidney, in epithelial cells. {ECO:0000269PubMed:16365161}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
1 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:2446166
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InterPro |
IPR008253
Marvel domain
IPR010844
Occludin/RNA polymerase II elongation factor, ELL domain
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PFAM |
PF01284
PF07303
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q3UZP0
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PhosphoSite |
PhosphoSite-Q3UZP0
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TrEMBL |
A3KML9
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UniProt Splice Variant |
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Entrez Gene |
218518
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UniGene |
Mm.401839
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RefSeq |
NP_001033691
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MGI ID |
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MGI Symbol |
Marveld2
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OMIM |
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CCDS |
CCDS26732
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HPRD |
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IMGT |
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EMBL |
AB219935
AK133741
BC003296
BC049919
BC132330
BC132356
DQ143929
DQ682659
DQ682660
DQ682661
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GenPept |
AAH03296
AAH49919
AAI32331
AAI32357
ABA18656
ABG89107
ABG89108
ABG89109
BAE21816
BAE54512
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