Version 5.4
Mus musculus Protein: Klk1
Summary
InnateDB Protein IDBP-178420.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Klk1
Protein Name kallikrein 1
Synonyms 0610007D04Rik; Kal; Klk1b6; Klk6; mGk-6;
Species Mus musculus
Ensembl Protein ENSMUSP00000074659
InnateDB Gene IDBG-178418 (Klk1)
Protein Structure
UniProt Annotation
Function Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis
Cellular Component
Protein Structure and Domains
PDB ID MGI:102850
InterPro IPR001254 Peptidase S1
IPR001314 Peptidase S1A, chymotrypsin-type
IPR009003 Trypsin-like cysteine/serine peptidase domain
PFAM PF00089
PRINTS PR00722
PIRSF
SMART SM00020
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P15947
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 16612
UniGene
RefSeq NP_034769
MGI ID
MGI Symbol Klk1
OMIM
CCDS CCDS21202
HPRD
IMGT
EMBL AK002278 BC010754 BC027736 BC053697 D10464 M13498 M13499 M13500
GenPept AAG11389 AAH10754 AAH27736 AAH53697 BAA01257 BAB21982

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca