Version 5.4
Mus musculus Protein: Rnf220
Summary
InnateDB Protein IDBP-179721.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rnf220
Protein Name ring finger protein 220
Synonyms 4732477A13; 4931406I20Rik; 5730503K05Rik; AV302541;
Species Mus musculus
Ensembl Protein ENSMUSP00000099751
InnateDB Gene IDBG-179719 (Rnf220)
Protein Structure
UniProt Annotation
Function E3 ubiquitin-protein ligase that promotes the ubiquitination and proteasomal degradation of SIN3B. {ECO:0000269PubMed:20170641}.
Subcellular Localization Cytoplasm {ECO:0000269PubMed:20170641}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016874 ligase activity
Biological Process
GO:0016567 protein ubiquitination
GO:0051865 protein autoubiquitination
Cellular Component
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:1913993
InterPro IPR001841 Zinc finger, RING-type
IPR011650 Peptidase M20, dimerisation domain
PFAM PF13639
PF14634
PF07687
PRINTS
PIRSF
SMART SM00184
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6PDX6
PhosphoSite PhosphoSite-Q6PDX6
TrEMBL
UniProt Splice Variant
Entrez Gene 66743
UniGene Mm.318331
RefSeq XP_006503352
MGI ID
MGI Symbol Rnf220
OMIM
CCDS
HPRD
IMGT
EMBL AK041785 AK172415 AL645740 AL844169 BC034875 BC056359 BC058415
GenPept AAH34875 AAH56359 AAH58415 BAE20604 BAE42996 CAM20837 CAM20839 CAM23616

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca