Mus musculus Protein: Hoxd13
Summary
InnateDB Protein IDBP-180968.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Hoxd13
Protein Name homeobox D13
Synonyms Hox-4.8; spdh;
Species Mus musculus
Ensembl Protein ENSMUSP00000001872
InnateDB Gene IDBG-180966 (Hoxd13)
Protein Structure
UniProt Annotation
Function Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
Subcellular Localization Nucleus.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0001501 skeletal system development
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007389 pattern specification process
GO:0009952 anterior/posterior pattern specification
GO:0022612 gland morphogenesis
GO:0030326 embryonic limb morphogenesis
GO:0030539 male genitalia development
GO:0035108 limb morphogenesis
GO:0042127 regulation of cell proliferation
GO:0042733 embryonic digit morphogenesis
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0048619 embryonic hindgut morphogenesis
GO:0060527 prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis
GO:0060571 morphogenesis of an epithelial fold
GO:0060602 branch elongation of an epithelium
GO:0060687 regulation of branching involved in prostate gland morphogenesis
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID MGI:96205
InterPro IPR001356 Homeobox domain
IPR009057 Homeodomain-like
IPR022067 Homeobox protein Hox1A3 N-terminal
PFAM PF00046
PF12284
PRINTS
PIRSF
SMART SM00389
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P70217
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 15433
UniGene Mm.57227
RefSeq NP_032301
MGI ID
MGI Symbol Hoxd13
OMIM
CCDS CCDS16139
HPRD
IMGT
EMBL AL928644 BC109143 BC109144 S80553 X99291
GenPept AAB21366 CAA67675 CAM20525