Mus musculus Protein: Hoxd8
Summary
InnateDB Protein IDBP-181131.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Hoxd8
Protein Name homeobox D8
Synonyms 4921540P06Rik; AI047735; Hox-4.3; Hox-5.4;
Species Mus musculus
Ensembl Protein ENSMUSP00000019749
InnateDB Gene IDBG-181129 (Hoxd8)
Protein Structure
UniProt Annotation
Function Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
Subcellular Localization Nucleus.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0009952 anterior/posterior pattern specification
GO:0048705 skeletal system morphogenesis
Cellular Component
GO:0005575 cellular_component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID MGI:96209
InterPro IPR001356 Homeobox domain
IPR009057 Homeodomain-like
IPR020479 Homeodomain, metazoa
PFAM PF00046
PRINTS PR00024
PIRSF
SMART SM00389
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P23463
PhosphoSite PhosphoSite-
TrEMBL F6W963
UniProt Splice Variant
Entrez Gene 15437
UniGene Mm.407633
RefSeq NP_032302
MGI ID
MGI Symbol Hoxd8
OMIM
CCDS CCDS16143
HPRD
IMGT
EMBL AL928644 M87803 X56561
GenPept AAA37852 CAA39911 CAM20532