Version 5.4
Mus musculus Protein: Adora3
Summary
InnateDB Protein IDBP-183871.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol Adora3
Protein Name adenosine A3 receptor
Synonyms 1700001D09Rik; 4930578J19Rik; A3AR; A3R; AA3R; ARA3; Gpcr2;
Species Mus musculus
Ensembl Protein ENSMUSP00000010279
InnateDB Gene IDBG-183869 (Adora3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001609 G-protein coupled adenosine receptor activity
Biological Process
GO:0001973 adenosine receptor signaling pathway
GO:0002553 histamine secretion by mast cell
GO:0002687 positive regulation of leukocyte migration
GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling
GO:0043306 positive regulation of mast cell degranulation
GO:0050729 positive regulation of inflammatory response
GO:0050850 positive regulation of calcium-mediated signaling
GO:0070257 positive regulation of mucus secretion
Cellular Component
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0042629 mast cell granule
Protein Structure and Domains
PDB ID MGI:104847
InterPro IPR013106 Immunoglobulin V-set domain
PFAM PF07686
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL G3X8R9
UniProt Splice Variant
Entrez Gene 11542
UniGene
RefSeq NP_081301
MGI ID
MGI Symbol Adora3
OMIM
CCDS CCDS38582
HPRD
IMGT
EMBL AC121847 CH466608
GenPept EDL07540

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca