InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Slitrk1

Summary

InnateDB Protein

IDBP-185902.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Slitrk1

Protein Name

SLIT and NTRK-like family, member 1

Synonyms

3200001I04Rik;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000097897

InnateDB Gene

IDBG-185900 (Slitrk1)

Protein Structure

UniProt Annotation

Function

Enhances neuronal dendrite outgrowth. {ECO:0000269PubMed:14550773}.

Subcellular Localization

Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.

Disease Associations

Tissue Specificity

In the adult, significant expression is detected only in the brain. Broadly expressed in embryonic brain with highest expression in subventricular zone, subplate, cortical plate, pyramidal cell layer of hippocampus, thalamus and hypothalamus where levels are highest in ventromedial hypothalamus and medial part of periaqueductal gray matter. Also expressed in mantle layer of spinal cord and in lateral and medial motor columns. {ECO:0000269PubMed:14550773}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	0
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0005515	protein binding

Biological Process

GO:0007399	nervous system development
GO:0007409	axonogenesis
GO:0030534	adult behavior
GO:0035264	multicellular organism growth
GO:0042592	homeostatic process