InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Lum

Summary

InnateDB Protein

IDBP-187529.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Lum

Protein Name

lumican

Synonyms

Ldc; SLRR2D;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000040877

InnateDB Gene

IDBG-187527 (Lum)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Secreted, extracellular space, extracellular matrix {ECO:0000250}.

Disease Associations

Tissue Specificity

Cornea and other tissues.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Experimentally validated
Total	5 [view]
Protein-Protein	5 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0005518	collagen binding

Biological Process

GO:0007601	visual perception
GO:0014070	response to organic cyclic compound
GO:0030199	collagen fibril organization
GO:0045087	innate immune response (InnateDB)
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0051216	cartilage development
GO:0070848	response to growth factor

Cellular Component

GO:0005578	proteinaceous extracellular matrix
GO:0005583	fibrillar collagen trimer
GO:0005615	extracellular space
GO:0031012	extracellular matrix
GO:0070062	extracellular vesicular exosome