Version 5.4
Mus musculus Protein: Csf3r
Summary
InnateDB Protein IDBP-187640.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Csf3r
Protein Name colony stimulating factor 3 receptor (granulocyte)
Synonyms Cd114; Csfgr; G-CSF-R; G-CSFR;
Species Mus musculus
Ensembl Protein ENSMUSP00000030673
InnateDB Gene IDBG-187638 (Csf3r)
Protein Structure
UniProt Annotation
Function Receptor for granulocyte colony-stimulating factor (CSF3). In addition it may function in some adhesion or recognition events at the cell surface.
Subcellular Localization Membrane; Single-pass type I membrane protein.
Disease Associations
Tissue Specificity Found in bone marrow.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
They are also associated with 20 interaction(s) predicted by orthology.
Experimentally validated
Total 11 [view]
Protein-Protein 9 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 20 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004896 cytokine receptor activity
GO:0005515 protein binding
Biological Process
GO:0007155 cell adhesion
GO:0019221 cytokine-mediated signaling pathway
GO:0030593 neutrophil chemotaxis
GO:0042475 odontogenesis of dentin-containing tooth
Cellular Component
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:1339755
InterPro IPR003961 Fibronectin, type III
IPR010457 Immunoglobulin C2-set-like, ligand-binding
PFAM PF00041
PF01108
PF06328
PRINTS
PIRSF
SMART SM00060
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P40223
PhosphoSite PhosphoSite-P40223
TrEMBL
UniProt Splice Variant
Entrez Gene 12986
UniGene Mm.490121
RefSeq XP_006502771
MGI ID 1PGR
MGI Symbol Csf3r
OMIM
CCDS CCDS18640
HPRD
IMGT
EMBL AL627101 M58288
GenPept AAA37673 CAM15033

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca