InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: P2rx2

Summary

InnateDB Protein

IDBP-189843.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

P2rx2

Protein Name

purinergic receptor P2X, ligand-gated ion channel, 2

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000054233

InnateDB Gene

IDBG-189841 (P2rx2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001614	purinergic nucleotide receptor activity
GO:0003713	transcription coactivator activity
GO:0004931	extracellular ATP-gated cation channel activity
GO:0005216	ion channel activity
GO:0005507	copper ion binding
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0008144	drug binding
GO:0008270	zinc ion binding
GO:0015276	ligand-gated ion channel activity
GO:0016151	nickel cation binding
GO:0035091	phosphatidylinositol binding
GO:0042802	identical protein binding
GO:0045340	mercury ion binding
GO:0046870	cadmium ion binding
GO:0050897	cobalt ion binding

Biological Process

GO:0001666	response to hypoxia
GO:0003029	detection of hypoxic conditions in blood by carotid body chemoreceptor signaling
GO:0006811	ion transport
GO:0006812	cation transport
GO:0007268	synaptic transmission
GO:0007274	neuromuscular synaptic transmission
GO:0007528	neuromuscular junction development
GO:0007605	sensory perception of sound
GO:0009743	response to carbohydrate
GO:0010033	response to organic substance
GO:0014832	urinary bladder smooth muscle contraction
GO:0019228	neuronal action potential
GO:0030432	peristalsis
GO:0033198	response to ATP
GO:0034220	ion transmembrane transport
GO:0035590	purinergic nucleotide receptor signaling pathway
GO:0048266	behavioral response to pain
GO:0048741	skeletal muscle fiber development
GO:0050909	sensory perception of taste
GO:0051260	protein homooligomerization
GO:0051291	protein heterooligomerization
GO:2001141	regulation of RNA biosynthetic process

Cellular Component

GO:0005622	intracellular
GO:0005639	integral component of nuclear inner membrane
GO:0005886	plasma membrane
GO:0005887	integral component of plasma membrane
GO:0009986	cell surface
GO:0014069	postsynaptic density
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0016324	apical plasma membrane
GO:0042734	presynaptic membrane
GO:0043025	neuronal cell body
GO:0043195	terminal bouton
GO:0043197	dendritic spine
GO:0043235	receptor complex