InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Cdh3

Summary

InnateDB Protein

IDBP-189958.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Cdh3

Protein Name

cadherin 3

Synonyms

AI385538; Cadp; Cdhp; P-cadherin; Pcad;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000079613

InnateDB Gene

IDBG-189956 (Cdh3)

Protein Structure

UniProt Annotation

Function

Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.

Subcellular Localization

Cell membrane; Single-pass type I membrane protein.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.

Predicted by orthology
Total	9 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005509	calcium ion binding

Biological Process

GO:0001895	retina homeostasis
GO:0007156	homophilic cell adhesion
GO:0010628	positive regulation of gene expression
GO:0010838	positive regulation of keratinocyte proliferation
GO:0016337	single organismal cell-cell adhesion
GO:0022405	hair cycle process
GO:0031424	keratinization
GO:0032773	positive regulation of monophenol monooxygenase activity
GO:0032912	negative regulation of transforming growth factor beta2 production
GO:0042060	wound healing
GO:0042493	response to drug
GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway
GO:0048023	positive regulation of melanin biosynthetic process
GO:0051796	negative regulation of catagen
GO:0060070	canonical Wnt signaling pathway
GO:0060901	regulation of hair cycle by canonical Wnt signaling pathway
GO:1902910	positive regulation of melanosome transport