InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Atp1b3

Summary

InnateDB Protein

IDBP-191964.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Atp1b3

Protein Name

ATPase, Na+/K+ transporting, beta 3 polypeptide

Synonyms

AA409958; AI664000; AW212096;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000034983

InnateDB Gene

IDBG-191962 (Atp1b3)

Protein Structure

UniProt Annotation

Function

This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-3 subunit is not known.

Subcellular Localization

Cell membrane; Single-pass type II membrane protein. Melanosome {ECO:0000250}.

Disease Associations

Tissue Specificity

Widely expressed.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.

Predicted by orthology
Total	6 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005391	sodium:potassium-exchanging ATPase activity
GO:0005515	protein binding

Biological Process

GO:0006813	potassium ion transport
GO:0006814	sodium ion transport
GO:0030001	metal ion transport
GO:0035725	sodium ion transmembrane transport

Cellular Component

GO:0005737	cytoplasm
GO:0005886	plasma membrane
GO:0005890	sodium:potassium-exchanging ATPase complex
GO:0005901	caveola
GO:0042470	melanosome
GO:0070062	extracellular vesicular exosome