Mus musculus Gene: Atp1b3
Summary
InnateDB Gene IDBG-191962.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Atp1b3
Gene Name ATPase, Na+/K+ transporting, beta 3 polypeptide
Synonyms AA409958; AI664000; AW212096;
Species Mus musculus
Ensembl Gene ENSMUSG00000032412
Encoded Proteins
ATPase, Na+/K+ transporting, beta 3 polypeptide
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000069849:
The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 3 subunit. This gene encodes a beta 3 subunit. A pseudogene exists for this gene, and it is located on chromosome 2. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:96332655-96364442
Strand Reverse strand
Band E3.3
Transcripts
ENSMUST00000034983 ENSMUSP00000034983
ENSMUST00000190045
ENSMUST00000187341
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005391 sodium:potassium-exchanging ATPase activity
GO:0005515 protein binding
Biological Process
GO:0006813 potassium ion transport
GO:0006814 sodium ion transport
GO:0030001 metal ion transport
GO:0035725 sodium ion transmembrane transport
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005890 sodium:potassium-exchanging ATPase complex
GO:0005901 caveola
GO:0042470 melanosome
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Hemostasis pathway
Cell surface interactions at the vascular wall pathway
Basigin interactions pathway
Ion channel transport pathway
Transmembrane transport of small molecules pathway
Ion transport by P-type ATPases pathway
KEGG
Cardiac muscle contraction pathway
Aldosterone-regulated sodium reabsorption pathway
Proximal tubule bicarbonate reclamation pathway
Salivary secretion pathway
Gastric acid secretion pathway
Pancreatic secretion pathway
Carbohydrate digestion and absorption pathway
Protein digestion and absorption pathway
Bile secretion pathway
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Transmembrane transport of small molecules pathway
Ion transport by P-type ATPases pathway
Basigin interactions pathway
Ion channel transport pathway
Cell surface interactions at the vascular wall pathway
Hemostasis pathway
Cell surface interactions at the vascular wall pathway
Ion channel transport pathway
Basigin interactions pathway
Hemostasis pathway
Transmembrane transport of small molecules pathway
Ion transport by P-type ATPases pathway
KEGG
Cardiac muscle contraction pathway
Aldosterone-regulated sodium reabsorption pathway
Proximal tubule bicarbonate reclamation pathway
Salivary secretion pathway
Gastric acid secretion pathway
Pancreatic secretion pathway
Carbohydrate digestion and absorption pathway
Protein digestion and absorption pathway
Bile secretion pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt P97370
TrEMBL Q3UFH4 Q544Q7 Q71VC6
UniProt Splice Variant
Entrez Gene 11933
UniGene Mm.424
RefSeq NM_007502
OMIM
CCDS CCDS23414
HPRD
IMGT
MGI ID MGI:107788
MGI Symbol Atp1b3
EMBL AF016510 AF140023 AF140024 AF140025 AF140026 AF140027 AF140028 AF140029 AK032516 AK148495 AK151700 AK159532 AK168273 BC079916 CH466560 U59761
GenPept AAB69866 AAC00019 AAD34544 AAH79916 BAC27906 BAE28587 BAE30623 BAE35160 BAE40219 EDL20954
RNA Seq Atlas 11933