InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Aldh2

Summary

InnateDB Protein

IDBP-197421.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Aldh2

Protein Name

aldehyde dehydrogenase 2, mitochondrial

Synonyms

Ahd-5; Ahd5;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000031411

InnateDB Gene

IDBG-197419 (Aldh2)

Protein Structure

UniProt Annotation

Function

Is capable of converting retinaldehyde to retinoic acid.

Subcellular Localization

Mitochondrion matrix.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.

Experimentally validated
Total	14 [view]
Protein-Protein	14 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	19 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004029	aldehyde dehydrogenase (NAD) activity
GO:0005515	protein binding
GO:0016491	oxidoreductase activity

Biological Process

GO:0006068	ethanol catabolic process
GO:0008152	metabolic process
GO:0055114	oxidation-reduction process

Cellular Component

GO:0005739	mitochondrion
GO:0005759	mitochondrial matrix

Protein Structure and Domains

PDB ID

MGI:99600

InterPro

IPR015590 Aldehyde dehydrogenase domain
IPR016161 Aldehyde/histidinol dehydrogenase

PFAM

PF00171

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P47738

PhosphoSite

PhosphoSite-P47738

TrEMBL

Q544B1

UniProt Splice Variant

Entrez Gene

11669

UniGene

Mm.284446

RefSeq

NP_033786

MGI ID

MGI Symbol

Aldh2

OMIM

CCDS

CCDS19638

HPRD

IMGT

EMBL

AK035145 AK042326 AK079602 AK150233 AK165032 BC005476 CH466529 S71509 U07235 Z32545

GenPept

AAA64636 AAC60691 AAH05476 BAC28959 BAC31225 BAC37697 BAE29398 BAE38010 EDL19720