InnateDB Protein
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IDBP-199429.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Bsn
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Protein Name
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bassoon
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Synonyms
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000035208
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InnateDB Gene
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IDBG-199427 (Bsn)
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Protein Structure
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Function |
Is thought to be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. Seems to act through binding to ERC2/CAST1. Essential in regulated neurotransmitter release from a subset of brain glutamatergic synapses (By similarity). Involved in the formation of the retinal photoreceptor ribbon synapses. {ECO:0000250, ECO:0000269PubMed:12628168, ECO:0000269PubMed:12628169}.
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Subcellular Localization |
Cytoplasm. Cell junction, synapse, synaptosome. Cytoplasm, cytoskeleton. Note=Localized to the active zone of presynaptic density.
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Disease Associations |
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Tissue Specificity |
Expressed in brain and retina. {ECO:0000269PubMed:12628168, ECO:0000269PubMed:12628169}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated |
Total |
4
[view]
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Protein-Protein |
4
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
6 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1277955
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InterPro |
IPR008899
Zinc finger, piccolo-type
IPR011011
Zinc finger, FYVE/PHD-type
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PFAM |
PF05715
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
O88737
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PhosphoSite |
PhosphoSite-O88737
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TrEMBL |
Q3UXD6
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UniProt Splice Variant |
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Entrez Gene |
12217
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UniGene |
Mm.20425
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RefSeq |
NP_031593
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MGI ID |
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MGI Symbol |
Bsn
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OMIM |
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CCDS |
CCDS23517
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HPRD |
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IMGT |
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EMBL |
AC137678
AC168217
AK129141
AK135719
Y17034
Y17035
Y17036
Y17037
Y17038
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GenPept |
BAC97951
BAE22627
CAA76598
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