Version 5.4
Mus musculus Gene: Bsn
Summary
InnateDB Gene IDBG-199427.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Bsn
Gene Name bassoon
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000032589
Encoded Proteins
IDBP-199429
bassoon
IDBP-787619
bassoon
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000164061:
Neurotransmitters are released from a specific site in the axon terminal called the active zone, which is composed of synaptic vesicles and a meshwork of cytoskeleton underlying the plasma membrane. The protein encoded by this gene is thought to be a scaffolding protein involved in organizing the presynaptic cytoskeleton. The gene is expressed primarily in neurons in the brain. A similar gene product in rodents is concentrated in the active zone of axon terminals and tightly associated with cytoskeletal structures, and is essential for regulating neurotransmitter release from a subset of synapses. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:108096022-108190384
Strand Reverse strand
Band F1
Transcripts
ENSMUST00000035208 ENSMUSP00000035208
ENSMUST00000124763 ENSMUSP00000139053
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0015630 microtubule cytoskeleton
GO:0019898 extrinsic component of membrane
GO:0030054 cell junction
GO:0030424 axon
GO:0030425 dendrite
GO:0044306 neuron projection terminus
GO:0045202 synapse
GO:0048786 presynaptic active zone
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000164061
View Gene Order
ENSBTAG00000011581
Not yet available
Cross-References
SwissProt O88737
TrEMBL Q3UXD6
UniProt Splice Variant
Entrez Gene 12217
UniGene Mm.20425
RefSeq NM_007567 XM_006511634
OMIM
CCDS CCDS23517
HPRD
IMGT
MGI ID MGI:1277955
MGI Symbol Bsn
EMBL AC137678 AC168217 AK129141 AK135719 Y17034 Y17035 Y17036 Y17037 Y17038
GenPept BAC97951 BAE22627 CAA76598
RNA Seq Atlas 12217

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca