InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Nup133

Summary

InnateDB Protein

IDBP-199806.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Nup133

Protein Name

nucleoporin 133

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000048084

InnateDB Gene

IDBG-199804 (Nup133)

Protein Structure

UniProt Annotation

Function

Involved in poly(A)+ RNA transport. {ECO:0000250UniProtKB:Q8WUM0}.

Subcellular Localization

Nucleus, nuclear pore complex {ECO:0000250}. Chromosome, centromere, kinetochore {ECO:0000250}. Note=Located on both the cytoplasmic and nuclear sides of the nuclear pore. During mitosis, localizes to the kinetochores (By similarity). {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 26 interaction(s) predicted by orthology.

Experimentally validated
Total	6 [view]
Protein-Protein	6 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	26 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005487	nucleocytoplasmic transporter activity
GO:0005515	protein binding

Biological Process

GO:0006406	mRNA export from nucleus
GO:0006999	nuclear pore organization
GO:0015031	protein transport
GO:0048339	paraxial mesoderm development

Cellular Component

GO:0000777	condensed chromosome kinetochore
GO:0000940	condensed chromosome outer kinetochore
GO:0005643	nuclear pore
GO:0016020	membrane
GO:0031080	nuclear pore outer ring