InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: LSM3

Summary

InnateDB Protein

IDBP-20053.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

LSM3

Protein Name

LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000302160

InnateDB Gene

IDBG-20051 (LSM3)

Protein Structure

UniProt Annotation

Function

Binds specifically to the 3'-terminal U-tract of U6 snRNA.

Subcellular Localization

Nucleus {ECO:0000305}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 57 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	57 [view]
Protein-Protein	53 [view]
Protein-DNA	4 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0000398	mRNA splicing, via spliceosome
GO:0006397	mRNA processing
GO:0010467	gene expression
GO:0016070	RNA metabolic process
GO:0016071	mRNA metabolic process
GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay