InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: P4ha3

Summary

InnateDB Protein

IDBP-201152.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

P4ha3

Protein Name

procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide III

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000055297

InnateDB Gene

IDBG-201148 (P4ha3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004656	procollagen-proline 4-dioxygenase activity
GO:0005506	iron ion binding
GO:0016491	oxidoreductase activity
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0016706	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0031418	L-ascorbic acid binding

Biological Process

GO:0019511	peptidyl-proline hydroxylation
GO:0055114	oxidation-reduction process

Cellular Component

GO:0005575	cellular_component
GO:0005783	endoplasmic reticulum

Protein Structure and Domains

PDB ID

MGI:2444049

InterPro

IPR005123 Oxoglutarate/iron-dependent dioxygenase
IPR006620 Prolyl 4-hydroxylase, alpha subunit
IPR013547 Prolyl 4-hydroxylase alpha-subunit, N-terminal

PFAM

PF03171
PF13640
PF08336

PRINTS

PIRSF

SMART

SM00702

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite