Version 5.4
Mus musculus Protein: Clip2
Summary
InnateDB Protein IDBP-202873.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Clip2
Protein Name CAP-GLY domain containing linker protein 2
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000098212
InnateDB Gene IDBG-202871 (Clip2)
Protein Structure
UniProt Annotation
Function Seems to link microtubules to dendritic lamellar body (DLB), a membranous organelle predominantly present in bulbous dendritic appendages of neurons linked by dendrodendritic gap junctions. May operate in the control of brain-specific organelle translocations (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Associated with the cytoskeleton. {ECO:0000250}.
Disease Associations
Tissue Specificity Expressed in the brain, and very low levels in kidneys. {ECO:0000269PubMed:9427243}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0051010 microtubule plus-end binding
Biological Process
GO:0016192 vesicle-mediated transport
Cellular Component
GO:0005881 cytoplasmic microtubule
GO:0016020 membrane
GO:0035371 microtubule plus-end
Protein Structure and Domains
PDB ID MGI:1313136
InterPro IPR000938 CAP Gly-rich domain
IPR010989 t-SNARE
PFAM PF01302
PRINTS
PIRSF
SMART SM01052
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9Z0H8
PhosphoSite PhosphoSite-Q9Z0H8
TrEMBL
UniProt Splice Variant
Entrez Gene 269713
UniGene Mm.255138
RefSeq NP_034120
MGI ID
MGI Symbol Clip2
OMIM
CCDS CCDS39310
HPRD
IMGT
EMBL AF289664 AF289667 AJ228863 AJ228865 AJ228866 AJ228867 AJ228868 AJ228869 AJ228870 AJ228871 AJ228872 AJ228873 AJ228874 AJ228875 AJ228876 AJ228877 AJ228878 AJ228879 AJ228880 BC039162 BC053048
GenPept AAF99333 AAF99340 AAH39162 AAH53048 CAA13068 CAA13069

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca