Version 5.4
Mus musculus Protein: Duoxa1
Summary
InnateDB Protein IDBP-202905.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Duoxa1
Protein Name dual oxidase maturation factor 1
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000028653
InnateDB Gene IDBG-202903 (Duoxa1)
Protein Structure
UniProt Annotation
Function May be required for the maturation and the transport from the endoplasmic reticulum to the plasma membrane of functional DUOX1. {ECO:0000250}.
Subcellular Localization Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0015031 protein transport
GO:0042743 hydrogen peroxide metabolic process
GO:0045666 positive regulation of neuron differentiation
GO:0050727 regulation of inflammatory response
GO:2000379 positive regulation of reactive oxygen species metabolic process
GO:2000609 regulation of thyroid hormone generation
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:2384861
InterPro IPR018469 Dual oxidase maturation factor
PFAM PF10204
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8VE49
PhosphoSite PhosphoSite-
TrEMBL A2AQ95
UniProt Splice Variant
Entrez Gene 213696
UniGene Mm.247121
RefSeq XP_006499157
MGI ID
MGI Symbol Duoxa1
OMIM
CCDS CCDS16661
HPRD
IMGT
EMBL AL844566 BC019755 CH466519
GenPept AAH19755 CAM16336 EDL28099

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca