InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ptcd1

Summary

InnateDB Protein

IDBP-208562.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ptcd1

Protein Name

pentatricopeptide repeat domain 1

Synonyms

1110069M14Rik;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000031628

InnateDB Gene

IDBG-208560 (Ptcd1)

Protein Structure

UniProt Annotation

Function

Mitochondrial protein implicated in negative regulation of leucine tRNA levels, as well as negative regulation of mitochondria-encoded proteins and COX activity. Affects also the 3'-processing of mitochondrial tRNAs. {ECO:0000250}.

Subcellular Localization

Mitochondrion {ECO:0000250}. Mitochondrion matrix {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000049	tRNA binding
GO:0003674	molecular_function

Biological Process

GO:0008150	biological_process
GO:0042780	tRNA 3'-end processing

Cellular Component

GO:0005759

mitochondrial matrix

Protein Structure and Domains

PDB ID

MGI:1919049

InterPro

IPR002885 Pentatricopeptide repeat

PFAM

PF01535
PF12854
PF13041
PF13812

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8C2E4

PhosphoSite

PhosphoSite-Q8C2E4

TrEMBL

UniProt Splice Variant

Entrez Gene

71799

UniGene

Mm.474456

RefSeq

NP_598496

MGI ID

MGI Symbol

Ptcd1

OMIM

CCDS

CCDS19858

HPRD

IMGT

EMBL

AK088764 AK171484 BC004766 BC083097

GenPept

AAH04766 AAH83097 BAC40555 BAE42485