InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Tob1

Summary

InnateDB Protein

IDBP-208790.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Tob1

Protein Name

transducer of ErbB-2.1

Synonyms

Tob; Trob;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000036039

InnateDB Gene

IDBG-208788 (Tob1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 43 interaction(s) predicted by orthology.

Experimentally validated
Total	6 [view]
Protein-Protein	6 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	43 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003714	transcription corepressor activity
GO:0005515	protein binding
GO:0030971	receptor tyrosine kinase binding
GO:0046332	SMAD binding

Biological Process

GO:0007184	SMAD protein import into nucleus
GO:0008285	negative regulation of cell proliferation
GO:0017148	negative regulation of translation
GO:0030514	negative regulation of BMP signaling pathway
GO:0045668	negative regulation of osteoblast differentiation
GO:0060212	negative regulation of nuclear-transcribed mRNA poly(A) tail shortening
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
GO:1900153	positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:2001141	regulation of RNA biosynthetic process