Version 5.4
Mus musculus Protein: Dusp15
Summary
InnateDB Protein IDBP-209933.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dusp15
Protein Name dual specificity phosphatase-like 15
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000045815
InnateDB Gene IDBG-209929 (Dusp15)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity Isoform 2 is highly expressed in testis. {ECO:0000269PubMed:11432789}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004725 protein tyrosine phosphatase activity
GO:0008138 protein tyrosine/serine/threonine phosphatase activity
Biological Process
GO:0006470 protein dephosphorylation
GO:0007179 transforming growth factor beta receptor signaling pathway
GO:0035335 peptidyl-tyrosine dephosphorylation
GO:0042127 regulation of cell proliferation
GO:0046330 positive regulation of JNK cascade
Cellular Component
GO:0005575 cellular_component
Protein Structure and Domains
PDB ID MGI:1934928
InterPro IPR000340 Dual specificity phosphatase, catalytic domain
IPR020417 Atypical dual specificity phosphatase
IPR020422 Dual specificity phosphatase, subgroup, catalytic domain
IPR029021 Protein-tyrosine phosphatase-like
PFAM PF00782
PRINTS PR01908
PIRSF
SMART SM00195
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8R4V2
PhosphoSite PhosphoSite-Q8R4V2
TrEMBL
UniProt Splice Variant
Entrez Gene 252864
UniGene
RefSeq NP_665687
MGI ID
MGI Symbol Dusp15
OMIM
CCDS CCDS16902
HPRD
IMGT
EMBL AF357887 AL833801 BC116841 BC116843 BU924460
GenPept AAI16842 AAI16844 AAM00226 CAM23680

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca